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This listing was closed on Aug 19, 2026.
Browse Open JobsSenior / Staff Machine Learning Research Engineer
Summary by AIEngineer.careers
Senior / Staff Machine Learning Research Engineer is a AI Research Engineer role (full-time). with Calico. in SOUTH SAN FRANCISCO, US. Compensation shown: $220K–$290K. Imported listing (source: jobs-radar.com). Apply on the employer's site (jobs-radar.com).
Imported listing (source: jobs-radar.com) · Apply on jobs-radar.com
SOUTH SAN FRANCISCO · US
$220K–$290K
Full-time
SENIOR
The sections below reproduce the third-party job description for reference. AIEngineer.careers does not write or control this text.
Imported job description
Sourced from jobs-radar.com
Calico seeks a Senior/Staff Machine Learning Research Engineer to lead ML research engineering for drug discovery. You will drive the engineering vision, optimize models on accelerators, and build evaluation frameworks to accelerate research impact.
Responsibilities
- Drive engineering vision for ML models from research to production
- Architect solutions for asynchronous execution, hardware orchestration, and high-throughput data pipelines
- Build foundational libraries enforcing software engineering rigor
- Translate prototype models (diffusion networks, vision transformers, DNA sequence models) into optimized JAX/PyTorch code
- Design evaluation frameworks, benchmarks, and scientific workflow tools
Requirements
- Strong intellectual curiosity for life sciences
- BS/MS with 7+ years or PhD with 4+ years of relevant ML software engineering experience
- Expertise in Python and JAX or PyTorch
- Hands-on experience building, training, or optimizing advanced ML architectures (transformers, diffusion networks, GNNs)
- Experience driving complex ML engineering projects from concept to production
Calico
South San Francisco · US · 498+ employees
Calico Life Sciences is a research and development company focused on understanding the biology of aging and age-related diseases. It integrates basic research, advanced computational biology, and drug development to create potential therapies that enable people to lead longer and healthier lives.
